Recent emphasis has been placed on the role that cerebellar dysfunctions could have in the genesis of cognitive deficits in Duchenne muscular dystrophy (DMD).However, relevant genotype-phenotype analyses are missing to define whether cerebellar defects underlie the severe cases of intellectual deficiency that have been associated with genetic loss
The Crouzon syndrome is a genetic disorder which is known as the brachial arch syndrome.It is an autosomal dominant disorder which is one of a rare napoleon concealer group of syndromes which is characterized by cranio synostosis or a premature closing of the cranial sutures.The major features are brachiocephaly, occular proptosis, an under develop
Autophagy is necessary for the degradation of long-lasting proteins and nonfunctional organelles, and is chainsaw file activated to promote cellular survival.However, overactivation of autophagy may deplete essential molecules and organelles responsible for cellular survival.Lifelong calorie restriction by 40% has been shown to increase the cardiac